SCHEMBL9214713

SCHEMBL9214713

[CH2]C(c1nc2ccccc2[nH]1)c1nc2ccccc2[nH]1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
POLB P06746 3/20 0.68
IDO1 P14902 1/20 0.68
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
NPSR1 Q6W5P4 2/20 0.56
KDM4E B2RXH2 1/20 0.56
ABCB11 O95342 1/20 0.56
TP53 P04637 1/20 0.56
PKM P14618 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TAAR1 Q96RJ0 1/20 0.54
MLKL Q8NB16 3/20 0.53
KMT2A Q03164 2/20 0.52
MASP2 O00187 1/20 0.52
MEN1 O00255 1/20 0.52
NUDT1 P36639 1/20 0.52
AOC3 Q16853 1/20 0.52
GAA P10253 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1099367 0.87 ALDH1A1 (0.58) ALDH1A1POLBIDO1NPC1RAB9A
SCHEMBL11021399 0.86 ALDH1A1 (0.61) ALDH1A1POLBIDO1NPC1RAB9A
SCHEMBL14128455 0.86 POLB (0.61) ALDH1A1POLBIDO1NPC1RAB9A
SCHEMBL28504834 0.82 MLKL (0.70) ALDH1A1POLBIDO1NPC1RAB9A
SCHEMBL4921708 0.81 IDO1 (1.00) ALDH1A1POLBIDO1NPC1RAB9A
SCHEMBL7531020 0.81 ALDH1A1 (0.66) ALDH1A1POLBIDO1NPC1RAB9A
SCHEMBL85832 0.81 ALDH1A1 (0.66) ALDH1A1POLBIDO1NPC1RAB9A
SCHEMBL7533794 0.81 ALDH1A1 (0.66) ALDH1A1POLBIDO1NPC1RAB9A
SCHEMBL2147079 0.81 ALDH1A1 (0.66) ALDH1A1POLBIDO1NPC1RAB9A
SCHEMBL7946544 0.81 IDO1 (0.78) ALDH1A1POLBIDO1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105367850-A Tire and method for manufacturing tire SUMITOMO RUBBER IND 2016-03-02 CN disclosed
CN-103703071-B Coupling agent for rubber/carbon black and rubber composition for tire containing the same SHIKOKU CHEMICALS CORP. (JP) 2015-12-09 CN disclosed
CN-103703071-A Coupling agent for rubber/carbon black and rubber composition for tire containing the same SHIKOKU CHEM 2014-04-02 CN disclosed
EP-0686151-A1 SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-12-13 EP disclosed