SCHEMBL11323975

SCHEMBL11323975

O=c1oc2ccccc2[nH]c1=S

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.61
ALDH1A1 P00352 6/20 0.61
GAA P10253 3/20 0.61
PSMB8 P28062 2/20 0.61
OGT O15294 1/20 0.61
F2 P00734 1/20 0.42
CFD P00746 1/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 5/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
POLB P06746 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6429912 0.81 OGT (0.63) KDM4EALDH1A1GAAPSMB8OGT
Benzoxazolinone SCHEMBL29475399 0.76 OGT (1.00) KDM4EALDH1A1GAAPSMB8OGT
SCHEMBL97140 0.76 PSMB8 (1.00) KDM4EALDH1A1GAAPSMB8OGT
Benzoxazolinone SCHEMBL19555 0.76 OGT (1.00) KDM4EALDH1A1GAAPSMB8OGT
Benzoxazolinone SCHEMBL9110846 0.76 OGT (1.00) KDM4EALDH1A1GAAPSMB8OGT
SCHEMBL30834681 0.76 PSMB8 (1.00) KDM4EALDH1A1GAAPSMB8OGT
Benzoxazolinone SCHEMBL3927631 0.76 OGT (1.00) KDM4EALDH1A1GAAPSMB8OGT
Benzoxazolinone SCHEMBL3650873 0.74 OGT (0.95) KDM4EALDH1A1GAAPSMB8OGT
Benzoxazolinone SCHEMBL28920994 0.74 OGT (0.95) KDM4EALDH1A1GAAPSMB8OGT
Benzoxazolinone SCHEMBL28598217 0.74 OGT (0.95) KDM4EALDH1A1GAAPSMB8OGT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4307091-A Process for treatment of allergic conditions with benzoxazinediones USV PHARMACEUTICAL CORPORATION (US) 1981-12-22 US disclosed