SCHEMBL97140

SCHEMBL97140

S=c1[nH]c2ccccc2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 14/20 1.00
KDM4E B2RXH2 2/20 1.00
GAA P10253 2/20 1.00
ALDH1A1 P00352 2/20 1.00
MAPT P10636 2/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
OGT O15294 1/20 0.56
KEAP1 Q14145 1/20 0.53
HSD17B10 Q99714 2/20 0.48
HTT P42858 1/20 0.48
CYP3A4 P08684 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30834681 1.00 PSMB8 (1.00) PSMB8KDM4EGAAALDH1A1MAPT
Phosphoric Acid SCHEMBL10490351 0.88 PSMB8 (0.78) PSMB8KDM4EGAAALDH1A1MAPT
SCHEMBL28808028 0.78 PSMB8 (0.60) PSMB8KDM4EGAAALDH1A1MAPT
SCHEMBL11323975 0.76 KDM4E (0.61) PSMB8KDM4EGAAALDH1A1MAPT
SCHEMBL4703352 0.74 KDM4E (0.75) PSMB8KDM4EGAAALDH1A1MAPT
SCHEMBL29747565 0.74 KDM4E (1.00) PSMB8KDM4EGAAALDH1A1MAPT
SCHEMBL4699050 0.74 KDM4E (1.00) PSMB8KDM4EGAAALDH1A1MAPT
SCHEMBL4698816 0.74 KDM4E (0.61) PSMB8KDM4EGAAALDH1A1MAPT
SCHEMBL12716526 0.73 KDM4E (0.82) PSMB8KDM4EGAAALDH1A1MAPT
SCHEMBL4237225 0.71 ALDH1A1 (0.56) PSMB8KDM4EGAAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 562 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105446080-B A kind of coating composition, its application and the substrate using it 深圳市容大感光科技股份有限公司 2019-11-08 CN claimed
WO-2016183101-A1 PALLADIUM-CATALYZED ARYLATION OF FLUOROALKYLAMINES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-11-17 WO claimed
CN-105446080-A Coating composition, application thereof and base material using same SHENZHEN RONGDA PHOTOSENSITIVE SCIENCE & TECH CO LTD 2016-03-30 CN claimed
US-9281000-B2 Photopolymer formulation for producing visible holograms COVESTRO DEUTSCHLAND AG (DE) 2016-03-08 US claimed
CN-102981366-A Solder-resistance composite and application to printed circuit board HUIZHOU CITY RONGDA PRINTING INK CO LTD 2013-03-20 CN claimed
CN-102643599-A UV (Ultraviolet)-thermoplastic resin composite laser aluminum-plated coating composition SHANGHAI WEIKAI CHEMICALS CO 2012-08-22 CN claimed
EP-2372454-A1 Photopolymer formulation for producing visible holograms Bayer MaterialScience AG (DE) 2011-10-05 EP claimed
US-20110236803-A1 PHOTOPOLYMER FORMULATION FOR PRODUCING VISIBLE HOLOGRAMS BAYER MATERIALSCIENCE AG (DE) 2011-09-29 US claimed
US-7655380-B2 Polymeric material, containing a latent acid CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-02-02 US claimed
US-7420060-B2 Benzopyran derivatives substituted with a thioxobenzoxazole derivative, pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containing them SCHAEFFLER KG (DE) 2008-09-02 US claimed
US-20070093481-A1 Benzopyran derivatives substituted with a thioxobenzoxazole derivative, pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containingthem DONGBU HANNONG CHEMICAL CO., LTD. (KR) 2007-04-26 US claimed
WO-2006027582-A1 ASSAY METHODS, MATERIALS AND PREPARATIONS AKUBIO LIMITED (GB) 2006-03-16 WO claimed
EP-1626968-A1 BENZOPYRAN DERIVATIVES SUBSTITUTED WITH A THIOXOBENZOXAZOLE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Dongbu Hannong Chemical Co., Ltd. (KR) 2006-02-22 EP claimed
WO-2004106331-A1 BENZOPYRAN DERIVATIVES SUBSTITUTED WITH A THIOXOBENZOXAZOLE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DONGBU HANNONG CHEMICAL CO., LTD (KR) 2004-12-09 WO claimed
EP-0393711-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1998-04-01 EP claimed
US-5204214-A Negative images with high contrast, sensitivity, dot image quality FUJI PHOTO FILM CO., LTD. (JP) 1993-04-20 US claimed
EP-0393711-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-10-24 EP claimed
US-4551419-A HIGH PHOTSENSITIVITY AND CONTRAST BY INCLUDING A SULFUR COMPOUND AND A MERCAPTO-CONTAINING AZAINDENE STABILIZER FUJI PHOTO FILM CO., LTD. (JP) 1985-11-05 US claimed
US-4216284-A NONDIFFUSIBLE SILVER BLEACH INHIBITOR FUJI PHOTO FILM CO., LTD. (JP) 1980-08-05 US claimed
US-4001020-A DEVELOPING A SILVER HA1IDE EMULSION IN CONTACT WITH A HETEROCYCLIC THIONE AND A POLYALKYLENE OXIDE FUJI PHOTO FILM CO., LTD. (JA) 1977-01-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070093481-A1 Benzopyran derivatives substituted with a thioxobenzoxazole derivative, pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containingthem TNNT2, TNNI3, BRIX1 PSMB8 2204/4885KDM4E 2853/4885GAA 1748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.