Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518976 | 0.83 | MCL1 (0.42) | MCL1MAPK1CYP2D6CA1CA2 | |
| SCHEMBL10971575 | 0.81 | MCL1 (0.37) | MCL1MAPK1CYP2D6KMT2ATLR4 | |
| SCHEMBL7904699 | 0.81 | MCL1 (0.40) | MCL1MAPK1CYP2D6CA1CA2 | |
| SCHEMBL535561 | 0.79 | MCL1 (0.49) | MCL1MAPK1CYP2D6CA1CA2 | |
| SCHEMBL535049 | 0.76 | MCL1 (0.46) | MCL1MAPK1CYP2D6CA1CA2 | |
| SCHEMBL900888 | 0.76 | MCL1 (0.49) | MCL1MAPK1CYP2D6CA1CA2 | |
| SCHEMBL28556596 | 0.76 | MCL1 (0.49) | MCL1MAPK1CYP2D6CA1CA2 | |
| SCHEMBL21751527 | 0.76 | MCL1 (0.49) | MCL1MAPK1CYP2D6CA1CA2 | |
| SCHEMBL16936484 | 0.74 | MCL1 (0.47) | MCL1MAPK1CYP2D6CA1CA2 | |
| SCHEMBL16291203 | 0.74 | MCL1 (0.47) | MCL1MAPK1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920042-A | Method for preparing alkane carboxylic acid by increasing alkane carbon chain | 北京岳达生物科技有限公司 | 2021-06-08 | — | — | CN | disclosed |
| CN-112888682-A | Heteroaryl aminoquinolines and analogs | 拜耳公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-110650628-A | Trisubstituted silylheteroaryloxyquinolines and analogs thereof | 拜耳公司 | 2020-01-03 | — | — | CN | disclosed |
| CN-110582484-A | Trisubstituted silylmethylphenoxyquinolines and analogs thereof | 拜耳公司 | 2019-12-17 | — | — | CN | disclosed |
| EP-2459546-B1 | NEW BICYCLIC DIOXANES, THEIR PREPARATION AND THEIR USE AS FRAGRANT COMPOUNDS | MANE FILS V (FR) | 2013-12-18 | — | — | EP | disclosed |
| US-8569518-B2 | Bicyclic dioxanes, their preparation and their use as fragrant compounds | V. MANE FILS (FR) | 2013-10-29 | — | — | US | disclosed |
| US-20120165557-A1 | New Bicyclic Dioxanes, Their Preparation and Their Use as Fragrant Compounds | V. MANE FILS (FR) | 2012-06-28 | — | — | US | disclosed |
| EP-2459546-A1 | NEW BICYCLIC DIOXANES, THEIR PREPARATION AND THEIR USE AS FRAGRANT COMPOUNDS | V. Mane Fils (FR) | 2012-06-06 | — | — | EP | disclosed |
| EP-2287159-A1 | New bicyclic dioxanes, their preparation and their use as organoleptic compounds | V.Mane Fils (FR) | 2011-02-23 | — | — | EP | disclosed |
| WO-2011013077-A1 | NEW BICYCLIC DIOXANES, THEIR PREPARATION AND THEIR USE AS FRAGRANT COMPOUNDS | V. MANE FILS (FR) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165557-A1 | New Bicyclic Dioxanes, Their Preparation and Their Use as Fragrant Compounds | CBR3, CCNT1, C1R | MCL1 1172/4885MAPK1 3434/4885CYP2D6 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.