Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132452 | 0.83 | MCL1 (0.45) | MCL1MAPK1CA1CA2CA4 | |
| SCHEMBL535049 | 0.81 | MCL1 (0.46) | MCL1MAPK1CA1CA2CA4 | |
| SCHEMBL16291203 | 0.79 | MCL1 (0.47) | MCL1MAPK1CA1CA2CA4 | |
| SCHEMBL535448 | 0.78 | LMNA (0.45) | MCL1MAPK1CA1CA2CA4 | |
| SCHEMBL2718691 | 0.77 | MCL1 (0.50) | MCL1MAPK1CA1CA2CA4 | |
| SCHEMBL535561 | 0.77 | MCL1 (0.49) | MCL1MAPK1CA1CA2CA4 | |
| SCHEMBL29191656 | 0.77 | NAAA (0.42) | MCL1MAPK1NPC1RAB9ATLR4 | |
| SCHEMBL10339687 | 0.76 | MCL1 (0.49) | MCL1MAPK1CA1CA2CA4 | |
| SCHEMBL5773706 | 0.76 | MCL1 (0.49) | MCL1MAPK1CA1CA2CA4 | |
| SCHEMBL9665167 | 0.75 | NAAA (0.45) | MCL1MAPK1TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154851-A | ANTIDEPRESSANTS, ANTIAGRESSIVE AGENTS | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-05-15 | — | — | US | disclosed |