SCHEMBL535049

SCHEMBL535049

CCCC(=O)C1CCCCC1=O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.46
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KMT2A Q03164 1/20 0.39
TLR4 O00206 5/20 0.38
GAA P10253 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL535116 0.94 HSD17B10 (0.43) MCL1MAPK1HSD17B10NPC1RAB9A
SCHEMBL535448 0.89 LMNA (0.45) MCL1MAPK1CA1CA2CA4
SCHEMBL29191656 0.88 NAAA (0.42) MCL1MAPK1NPC1RAB9AALDH1A1
SCHEMBL9665167 0.86 NAAA (0.45) MCL1MAPK1TLR4
SCHEMBL7762851 0.86 NAAA (0.45) MCL1MAPK1TLR4
SCHEMBL7757533 0.86 NAAA (0.45) MCL1MAPK1TLR4
SCHEMBL535561 0.85 MCL1 (0.49) MCL1MAPK1CA1CA2CA4
SCHEMBL535761 0.84 LMNA (0.46) MCL1MAPK1ALDH1A1TLR4
SCHEMBL16291203 0.83 MCL1 (0.47) MCL1MAPK1CA1CA2CA4
SCHEMBL27539994 0.82 TLR4 (0.42) ALDH1A1TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113620849-A Cyclohexenone compounds and preparation method and application thereof 山东海诺格生物科技有限公司 2021-11-09 CN disclosed
EP-1952918-B1 METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM TOYO INK MFG CO (JP) 2013-05-22 EP disclosed
US-8440110-B2 Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film TOYO INK MFG CO., LTD. (JP) 2013-05-14 US disclosed
EP-1990377-B1 COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION CONTAINING SAID COLORED METALLIC PIGMENT TOYO ALUMINIUM KK (JP) 2012-02-08 EP disclosed
US-20110295038-A1 Process for the Preparation of Substituted 1-aminomethyl-2-phenyl-cyclohexane Compounds GRUENENTHAL GMBH (DE) 2011-12-01 US disclosed
US-20110295038-A1 Process for the Preparation of Substituted 1-aminomethyl-2-phenyl-cyclohexane Compounds GRUENENTHAL GMBH (DE) 2011-12-01 US disclosed
US-7998266-B2 Colored metallic pigment, process for producing the same, and coating composition and cosmetic preparation containing said colored metallic pigment TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2011-08-16 US disclosed
US-20110175040-A1 METHOD FOR PRODUCING METAL PARTICLE DISPRESION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM TOYO INK MFG CO., LTD. (JP) 2011-07-21 US disclosed
US-7981327-B2 Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film TOYO INK MFG. CO. LTD. (JP) 2011-07-19 US disclosed
US-20090258202-A1 Method for Producing Metal Particle Dispersion, Conductive Ink Using Metal Particle Dispersion Produced by Such Method, and Conductive Coating Film GVP GESELLSCHAFT ZUR VERMARKTUNG DER PORENBRENNERTECHNIK MBH (DE) 2009-10-15 US disclosed
US-20090017082-A1 COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION CONTAINING SAID COLORED METALLIC PIGMENT TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2009-01-15 US disclosed
EP-1990377-A1 COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION COMPRISING SAID COLORED METALLIC PIGMENT TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2008-11-12 EP disclosed
EP-1952918-A1 METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM Toyo Ink Mfg. Co., Ltd (JP) 2008-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295038-A1 Process for the Preparation of Substituted 1-aminomethyl-2-phenyl-cyclohexane Compounds ADRM1, PNMT, ACMSD MCL1 612/4885MAPK1 1158/4885HSD17B10 3426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.