Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.55 |
| ▸ | KDM6A | O15550 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508846 | 0.83 | NPC1 (0.51) | KDM6BKDM6APTGS2RAB9ANPC1 | |
| SCHEMBL11326031 | 0.81 | KDM6B (0.55) | KDM6BKDM6APTGS2RAB9ANPC1 | |
| SCHEMBL11326079 | 0.77 | PTGS2 (0.62) | KDM6BKDM6APTGS2ESR1ESR2 | |
| SCHEMBL29531707 | 0.76 | NPC1 (0.69) | KDM6BKDM6ARAB9ANPC1ALDH1A1 | |
| SCHEMBL824375 | 0.76 | NPC1 (0.69) | KDM6BKDM6ARAB9ANPC1ALDH1A1 | |
| SCHEMBL12861182 | 0.76 | PTGS2 (0.60) | KDM6BKDM6APTGS2ESR1ESR2 | |
| SCHEMBL5831992 | 0.75 | PTGS2 (0.80) | KDM6BKDM6APTGS2ESR1ESR2 | |
| SCHEMBL24155763 | 0.75 | SMN1; SMN2 (0.58) | PTGS2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL22023371 | 0.75 | SMN1; SMN2 (0.58) | PTGS2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL1296601 | 0.74 | KDM6B (0.78) | KDM6BKDM6APTGS2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256626-A | 2-BENZIMIDAZOLYL-, 2-BENZOTHIAZOLYL-, OR 2-INDOLYL-PHENYL DERIVATIVES LINKED TO A 2-HYDROXYBENZOPHENONE | EASTMAN KODAK COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
| US-4174321-A | POLYMERIC MOLDING MATERIALS | EASTMAN KODAK COMPANY (US) | 1979-11-13 | — | — | US | disclosed |
| US-4127501-A | BENZOXAZOLE, BENZOTHIAZOLE, BENZIMIDAZOLE, BENZOTRIAZOLE OR INDOLE DERIVATIVES | EASTMAN KODAK COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
| US-4115348-A | DEGRADATION INHIBITORS | EASTMAN KODAK COMPANY (US) | 1978-09-19 | — | — | US | disclosed |