Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11324913 | 0.83 | KDM6B (0.55) | NPC1RAB9AALDH1A1MAPTHSD17B10 | |
| SCHEMBL29531707 | 0.82 | NPC1 (0.69) | NPC1RAB9AALDH1A1MAPTHSD17B10 | |
| SCHEMBL824375 | 0.82 | NPC1 (0.69) | NPC1RAB9AALDH1A1MAPTHSD17B10 | |
| SCHEMBL16459759 | 0.81 | NPC1 (0.67) | NPC1RAB9AALDH1A1MAPTHSD17B10 | |
| SCHEMBL9511174 | 0.81 | PIK3CG (0.53) | NPC1RAB9AALDH1A1MAPTHSD17B10 | |
| SCHEMBL2493869 | 0.79 | ALDH1A1 (0.56) | NPC1RAB9AALDH1A1MAPTHSD17B10 | |
| SCHEMBL5130815 | 0.78 | HSD17B10 (0.67) | NPC1RAB9AALDH1A1MAPTHSD17B10 | |
| SCHEMBL12861182 | 0.78 | PTGS2 (0.60) | NPC1RAB9AALDH1A1MAPTHSD17B10 | |
| SCHEMBL29529489 | 0.77 | NPC1 (0.55) | NPC1RAB9AALDH1A1MAPTHSD17B10 | |
| SCHEMBL13053009 | 0.77 | NPC1 (0.55) | NPC1RAB9AALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345513-B1 | POLYARYLENEETHERS HAVING BENZOXAZOLE GROUPS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1993-09-08 | — | — | EP | disclosed |
| US-4960855-A | Polyarylene ether containing benzoxazole groups and a process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |