Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.56 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2871612 | 0.85 | MME (0.68) | MMEALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL11331601 | 0.84 | CPB2 (0.59) | MMECPB2ACE | |
| SCHEMBL9067110 | 0.83 | MME (0.67) | MMEALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL11333911 | 0.82 | CPB2 (0.57) | MMECPB2ACEFOLH1 | |
| SCHEMBL11333671 | 0.82 | MME (0.50) | MME | |
| SCHEMBL11321753 | 0.81 | CPB2 (0.55) | MMECPB2ALDH1A1MEN1LMNA | |
| SCHEMBL11325107 | 0.81 | FNTA (0.53) | CPB2 | |
| SCHEMBL11433538 | 0.80 | MME (0.63) | MMEALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7431713 | 0.80 | FOLH1 (0.41) | MMEALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7431705 | 0.80 | FOLH1 (0.41) | MMEALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4284779-A | Amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1981-08-18 | — | — | US | disclosed |
| US-4284780-A | Amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1981-08-18 | — | — | US | disclosed |
| US-4179434-A | Amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4177277-A | INHIBITION OF ANGIOTENSIN-CONVERTING ENZYME | E. R. SQUIBB & SONS, INC. (US) | 1979-12-04 | — | — | US | disclosed |
| US-4165320-A | Amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-08-21 | — | — | US | disclosed |
| US-4156786-A | Amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4154960-A | Amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154946-A | Amino mercapto substituted acylamino acids | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4146611-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-03-27 | — | — | US | disclosed |
| US-4129571-A | Amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1978-12-12 | — | — | US | disclosed |
| US-4113715-A | Amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1978-09-12 | — | — | US | disclosed |