Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604288 | 0.91 | PSMB5 (0.53) | PSMB5HSD11B1GPR3RARB | |
| SCHEMBL9617751 | 0.88 | PSMB5 (0.51) | PSMB5HSD11B1GPR3CA1CA2 | |
| SCHEMBL23432416 | 0.86 | SKP2 (0.59) | PSMB5HSD11B1GPR3BACE1SKP2 | |
| SCHEMBL10654561 | 0.86 | PSMB5 (0.62) | PSMB5HSD11B1GPR3BACE1SKP2 | |
| SCHEMBL29100401 | 0.85 | CNR1 (0.48) | PSMB5BACE1CA1CA2ALDH1A1 | |
| SCHEMBL27836085 | 0.85 | PSMB5 (0.51) | PSMB5HSD11B1GPR3SKP2RARB | |
| SCHEMBL11512580 | 0.85 | HSD11B1 (0.62) | PSMB5HSD11B1CA1CA2RARB | |
| SCHEMBL29086650 | 0.85 | PSMB5 (0.51) | PSMB5HSD11B1GPR3RARBALDH1A1 | |
| SCHEMBL4591101 | 0.84 | BACE1 (0.66) | PSMB5HSD11B1BACE1HPGD | |
| SCHEMBL26193728 | 0.84 | RARB (0.55) | PSMB5HSD11B1GPR3BACE1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292462-A | INSULATORS-COOLANTS FOR TRANSFORMERS | RHONE-POULENC INDUSTRIES (FR) | 1981-09-29 | — | — | US | disclosed |
| US-4177156-A | SPECIALTY OILS FOR TRANSFORMERS | RHONE-POULENC INDUSTRIES (FR) | 1979-12-04 | — | — | US | disclosed |
| US-4119555-A | COOLANTS FOR TRANSFORMERS | RHONE-POULENC INDUSTRIES (FR) | 1978-10-10 | — | — | US | disclosed |