Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 3/20 | 0.39 |
| ▸ | FLT4 | P35916 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2291287 | 0.77 | SMN1; SMN2 (0.55) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL11325238 | 0.75 | POLB (0.41) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL11481511 | 0.70 | L3MBTL1 (0.49) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL10874236 | 0.67 | ALDH1A1 (0.52) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL10362600 | 0.67 | SMN1; SMN2 (0.52) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL11172530 | 0.66 | POLB (0.51) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL8196836 | 0.66 | SMN1; SMN2 (0.59) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL30209768 | 0.66 | SMN1; SMN2 (0.59) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL1924430 | 0.66 | ALDH1A1 (0.50) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL9114220 | 0.65 | TDP1 (0.50) | L3MBTL1POLBTHRBRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243678-A | GASTROINTESTINAL DISORDERS, LIVER DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-01-06 | — | — | US | disclosed |