Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203616 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPTPTGS1TSHRHIF1A | |
| SCHEMBL4526048 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPTPTGS1TSHRHPGD | |
| SCHEMBL1844869 | 0.74 | — | — | |
| SCHEMBL1844864 | 0.74 | — | — | |
| SCHEMBL27937957 | 0.72 | — | — | |
| SCHEMBL11360511 | 0.72 | — | — | |
| SCHEMBL2686144 | 0.71 | ALDH1A1 (0.42) | ALDH1A1MAPTPTGS1TSHRHIF1A | |
| SCHEMBL9307553 | 0.71 | ALDH1A1 (0.36) | ALDH1A1MAPTPTGS1TSHRHPGD | |
| SCHEMBL897666 | 0.69 | ALDH1A1 (0.39) | ALDH1A1MAPTPTGS1TSHRABCB11 | |
| SCHEMBL9866977 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277427-A | DISTRIBUTION OF RESINOUS FLAKES CONTAINING A BLOWING AGENT SUPPRESSOR ON A PRINTED, GELLED, FOAMABLE POLYMER | CONGOLEUM CORPORATION (US) | 1981-07-07 | — | — | US | disclosed |