Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 4/20 | 0.33 |
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.33 |
| ▸ | WEE1 | P30291 | 2/20 | 0.33 |
| ▸ | MYT1 | Q01538 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | HPD | P32754 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928607 | 0.83 | LMNA (0.37) | POLBLMNANPSR1 | |
| SCHEMBL8957033 | 0.77 | POLB (0.41) | POLBLMNANPSR1PKMYT1WEE1 | |
| SCHEMBL28002886 | 0.76 | LMNA (0.33) | LMNANPSR1 | |
| SCHEMBL11150924 | 0.76 | CYP1A2 (0.36) | POLBLMNACYP1A2 | |
| SCHEMBL11297530 | 0.74 | CYP3A4 (0.39) | POLBHTTLMNAMAPTCYP1A2 | |
| SCHEMBL2212267 | 0.73 | KDM4E (0.40) | POLBLMNANPSR1MAPTCYP1A2 | |
| SCHEMBL11042949 | 0.71 | KDM4E (0.53) | LMNAMAPT | |
| SCHEMBL7888426 | 0.71 | GRIN2D (0.41) | POLBLMNANPSR1MAPT | |
| SCHEMBL4968505 | 0.71 | POLB (0.36) | POLBLMNANPSR1MAPTBRD4 | |
| SCHEMBL4649792 | 0.71 | KDM4E (0.42) | POLBLMNANPSR1MAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283331-A | FIBER-REACTIVE DYES | CIBA-GEIGY CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4243809-A | 5-SULFONYL-6-HYDROXYPYRIDONES OR THE 3-CARBAMOYL DERIVATIVES; SULFONYLATION WITH AN ALKYL SULFONYL HALIDE | CIBA-GEIGY CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |