Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28859493 | 0.85 | KIF11 (0.56) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL28859464 | 0.84 | HTT (0.50) | SLC6A2SLC6A4SLC6A3TAS1R3TAS1R1 | |
| SCHEMBL28520323 | 0.84 | PDE4B (0.54) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL28859465 | 0.83 | CA1 (0.53) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL12226756 | 0.83 | CA1 (0.46) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL28718619 | 0.81 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3TAS1R3TAS1R1 | |
| SCHEMBL7105851 | 0.80 | CA1 (0.50) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL4932919 | 0.80 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3TAS1R3TAS1R1 | |
| SCHEMBL6824559 | 0.79 | SLC6A3 (0.55) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL13116471 | 0.79 | SLC6A2 (0.53) | SLC6A2SLC6A3HTTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306075-A | Composition and process | THE UPJOHN COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
| US-4306076-A | Inter-phenylene CBA compounds | THE UPJOHN COMPANY (US) | 1981-12-15 | — | — | US | disclosed |