Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | NAT1 | P18440 | 1/20 | 0.46 |
| ▸ | MAX | P61244 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752280 | 0.81 | HSD11B1 (0.61) | PIM1PIM2NAT1PARP1PARP10 | |
| SCHEMBL5752284 | 0.81 | HSD11B1 (0.61) | PIM1PIM2NAT1PARP1PARP10 | |
| SCHEMBL15828902 | 0.81 | KMT2A (0.58) | PIM1PIM2MAOBPARP1PARP10 | |
| SCHEMBL8828528 | 0.81 | HSD11B1 (0.61) | PIM1PIM2NAT1PARP1PARP10 | |
| SCHEMBL11325775 | 0.81 | CYP1A2 (0.59) | PIM1PIM2MAOBNAT1PARP1 | |
| SCHEMBL8883177 | 0.81 | CYP1A2 (0.59) | PIM1PIM2MAOBNAT1PARP1 | |
| SCHEMBL9139338 | 0.79 | MIF (0.48) | MAOBPARP1MAPTPDE4BMAOA | |
| SCHEMBL9139342 | 0.79 | MIF (0.48) | MAOBPARP1MAPTPDE4BMAOA | |
| SCHEMBL15940018 | 0.77 | MEN1 (0.53) | AKR1C3AKR1C1PIM1PIM2MAOB | |
| SCHEMBL15940019 | 0.77 | MEN1 (0.53) | AKR1C3AKR1C1PIM1PIM2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294827-A | CEPHALOSPORINS OR PENICILLINS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |