SCHEMBL11326257

SCHEMBL11326257

O=C1CN2C=CC=CC2=NC1=O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
HPGD P15428 3/20 0.43
KDM4E B2RXH2 3/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 2/20 0.36
POLB P06746 2/20 0.36
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL892819 0.79 ALDH1A1 (0.38) ALDH1A1HPGDKDM4EMEN1MAPT
Bromide SCHEMBL3576597 0.78 ALDH1A1 (0.37) ALDH1A1HPGDKDM4EMEN1MAPT
Hydrochloric Acid SCHEMBL3306488 0.78 ALDH1A1 (0.41) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL10028948 0.71 KDM4E (0.38) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL3457997 0.71 KDM4E (0.38) ALDH1A1HPGDKDM4EMEN1MAPT
Pentane SCHEMBL28765480 0.69 ALDH1A1 (0.33) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL2162391 0.68 ALDH1A1 (0.36) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL4554180 0.68 ALDH1A1 (0.36) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL11033640 0.64 KDM4E (0.33) ALDH1A1HPGDKDM4EHSD17B10POLB
SCHEMBL10134052 0.64 ALDH1A1 (0.31) ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4269914-A INCLUDING A LAYER TO RECEIVE AND IMMOBILIZE A DIFFUSIBLE DESENSITIZER ABLE TO EFFECT THE SENSITIVITY OF A SILVER HALIDE EMULSION TO ELECTROMAGNETIC RADIATION AND A BARRIER LAYER EASTMAN KODAK COMPANY (US) 1981-05-26 US disclosed
US-4223082-A ELECTROMAGNETIC WAVES EASTMAN KODAK COMPANY (US) 1980-09-16 US disclosed