Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3306488 | 0.98 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| Bromide SCHEMBL3576597 | 0.98 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| Pentane SCHEMBL28765480 | 0.88 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL2162391 | 0.79 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL11326257 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL10028948 | 0.74 | KDM4E (0.38) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL3457997 | 0.74 | KDM4E (0.38) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL2230323 | 0.74 | ALDH1A1 (0.30) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL15805618 | 0.72 | KDM4E (0.36) | ALDH1A1KDM4EHPGD | |
| SCHEMBL4554180 | 0.71 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109699-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2026-04-23 | — | — | US | claimed |
| CN-120129683-A | Azole derivatives as SHP2 inhibitors | IRBM股份公司 | 2025-06-10 | — | — | CN | claimed |
| US-20240239799-A1 | (S)-1-(5-((PYRIDIN-3-YL)THIO)PYRAZIN-2-YL)-4'H,6'H-SPIRO[PIPERIDINE-4,5'-PYRROLO [1,2-B]PYRAZOL]-4'-AMINE DERIVATIVES AND SIMILAR COMPOUNDS AS SHP2 INHIBITORS FOR THE TREATMENT OF E.G. CANCER | C.N.C.C.S. S.C.A.R.L. COLLEZIONE NAZIONALE DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) | 2024-07-18 | — | — | US | claimed |
| EP-4345101-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2024-04-03 | — | — | EP | claimed |
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| EP-1434552-A1 | METHOD FOR DYEING KERATINOUS FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-07-07 | — | — | EP | claimed |
| WO-2003030841-A1 | METHOD FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| EP-0329491-A2 | Photographic elements incorporating antihalation and/or acutance dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-08-23 | — | — | EP | claimed |
| EP-0101646-B1 | PHOTOGRAPHIC ELEMENTS INCORPORATING ANTIHALATION AND/OR ACUTANCE DYES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-02-17 | — | — | EP | claimed |
| US-4581325-A | Photographic elements incorporating antihalation and/or acutance dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-04-08 | — | — | US | claimed |
| US-4551413-A | USING OXONAL OR MEROCYANINE DYES; LASERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-11-05 | — | — | US | claimed |
| EP-0130213-A1 | RECORDING MEDIUM FOR OPTICAL DATA STORAGE. | MINNESOTA MINING & MFG (US) | 1985-01-09 | — | — | EP | claimed |
| WO-1984002794-A1 | RECORDING MEDIUM FOR OPTICAL DATA STORAGE | MINNESOTA MINING & MFG (US) | 1984-07-19 | — | — | WO | claimed |
| EP-0101646-A2 | Photographic elements incorporating antihalation and/or acutance dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-02-29 | — | — | EP | claimed |
| CN-122059955-A | Imidazo pyridone compound, photocatalysis continuous synthesis method and application thereof | 南京工业大学 | 2026-05-19 | — | — | CN | disclosed |
| US-20260109699-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2026-04-23 | — | — | US | disclosed |
| CN-120129683-A | Azole derivatives as SHP2 inhibitors | IRBM股份公司 | 2025-06-10 | — | — | CN | disclosed |
| US-3943142-A | Dye intermediates and their preparation and use in the synthesis of methine dyes | EASTMAN KODAK COMPANY (US) | 1976-03-09 | — | — | US | disclosed |
| US-3936308-A | Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus | EASTMAN KODAK COMPANY (US) | 1976-02-03 | — | — | US | disclosed |
| US-3935010-A | IMIDAZOQUINOXALINE DESENSITIZER | EASTMAN KODAK COMPANY (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | ALDH1A1 83/4885KDM4E 440/4885HPGD 125/4885 |
| US-20260109699-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | PTPN1, PTPN5, PTPN3 | ALDH1A1 2460/4885KDM4E 1329/4885HPGD 4547/4885 |
| US-20240239799-A1 | (S)-1-(5-((PYRIDIN-3-YL)THIO)PYRAZIN-2-YL)-4'H,6'H-SPIRO[PIPERIDINE-4,5'-PYRROLO [1,2-B]PYRAZOL]-4'-AMINE DERIVATIVES AND SIMILAR COMPOUNDS AS SHP2 INHIBITORS FOR THE TREATMENT OF E.G. CANCER | PTPN1, PTPN5, PTPRJ | ALDH1A1 2676/4885KDM4E 906/4885HPGD 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.