SCHEMBL11326481

SCHEMBL11326481

Cc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2C)n1

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.54
CA1 P00915 5/20 0.53
CA2 P00918 5/20 0.53
CA9 Q16790 5/20 0.53
CA12 O43570 3/20 0.53
GAA P10253 1/20 0.50
LMNA P02545 1/20 0.49
ALOX15 P16050 1/20 0.47
TSHR P16473 2/20 0.47
ALDH1A1 P00352 2/20 0.47
ALKBH2 Q6NS38 1/20 0.46
ALKBH3 Q96Q83 1/20 0.46
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11326475 1.00 FBP1 (0.54) FBP1CA1CA2CA9CA12
SCHEMBL11560856 0.89 GAA (0.55) FBP1CA1CA2CA9CA12
SCHEMBL27846320 0.88 GAA (0.49) GAALMNAALOX15TSHRALDH1A1
SCHEMBL9805001 0.88 GAA (0.49) CA1CA2CA9CA12GAA
SCHEMBL11094019 0.88 GAA (0.49) FBP1GAALMNAALOX15TSHR
SCHEMBL10650821 0.88 GAA (0.49) FBP1GAALMNAALOX15TSHR
SCHEMBL11637413 0.87 FBP1 (0.55) FBP1CA1CA2CA9CA12
SCHEMBL10957889 0.86 ALDH1A1 (0.59) CA1CA2CA9CA12GAA
SCHEMBL11106251 0.86 GAA (0.48) CA1CA2CA9CA12GAA
SCHEMBL10445078 0.86 GAA (0.45) FBP1CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4301286-A Herbicidal O-alkyl sulfonylisoureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-17 US disclosed
EP-0024215-A1 Herbicidal sulfonylisoureas, and compositions, preparation and use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-02-25 EP disclosed