SCHEMBL11326873

SCHEMBL11326873

CCCCCc1cc(=O)n(-c2ccc([N+](=O)[O-])cc2)[nH]1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.51
▸ KMT2A Q03164 6/20 0.51
▸ MAPT P10636 6/20 0.51
▸ LMNA P02545 3/20 0.51
▸ HTT P42858 3/20 0.51
▸ CYP1A2 P05177 1/20 0.51
▸ CYP3A4 P08684 1/20 0.51
▸ CYP2C9 P11712 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ RAB9A P51151 1/20 0.51
▸ KDM4E B2RXH2 2/20 0.49
▸ CDC7 O00311 1/20 0.49
▸ POLB P06746 1/20 0.45
▸ PLEC Q15149 1/20 0.45
▸ KCNH2 Q12809 2/20 0.42
▸ CDC25B P30305 3/20 0.41
▸ ALDH1A1 P00352 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ GSK3A P49840 1/20 0.38
▸ GSK3B P49841 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7518997 0.81 TSHR (0.55) MEN1KMT2AMAPTLMNAHTT
SCHEMBL11199820 0.80 TSHR (0.53) MEN1KMT2AMAPTLMNAKDM4E
SCHEMBL23400824 0.78 MAPT (0.43) MEN1KMT2AMAPTLMNAHTT
SCHEMBL23403253 0.76 TSHR (0.56) MEN1KMT2AMAPTLMNAHTT
SCHEMBL11424843 0.76 TSHR (0.47) MEN1KMT2AMAPTLMNAHTT
SCHEMBL11331216 0.76 ALKBH5 (0.40) MEN1KMT2AMAPTLMNAHTT
SCHEMBL11334354 0.75 KDM4E (0.44) MAPTLMNARAB9AKDM4ESMN1; SMN2
SCHEMBL11532160 0.75 MAPT (0.52) MEN1KMT2AMAPTLMNAHTT
SCHEMBL2435022 0.75 MAPT (0.61) MEN1KMT2AMAPTLMNAHTT
SCHEMBL7252625 0.74 MAPT (0.54) MEN1KMT2AMAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4304769-A PESTICIDES EASTMAN KODAK COMPANY (US) 1981-12-08 — — US disclosed
US-4258127-A PHOTOGRAPHY, FOGGING FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 — — US disclosed
US-4247627-A Photographic elements having hydrophilic colloid layers containing hydrophobic ultraviolet absorbers uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1981-01-27 — — US disclosed
US-4214047-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-07-22 — — US disclosed
US-4203716-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-05-20 — — US disclosed
US-4199363-A Processes for achieving uniform, efficient distribution of hydrophobic materials through hydrophilic colloid layers and loaded latex compositions EASTMAN KODAK COMPANY (US) 1980-04-22 — — US disclosed
US-RE28760-E Photographic element including superimposed silver halide layers of different speeds EASTMAN KODAK COMPANY (US) 1976-04-06 — — US disclosed
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