Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.68 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.68 |
| ▸ | BCL2 | P10415 | 3/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.58 |
| ▸ | LIG1 | P18858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077329 | 0.85 | GABRA1 (0.66) | GABRA1GABRB1BCL2MCL1LMNA | |
| SCHEMBL11758041 | 0.85 | GABRA1 (0.71) | GABRA1GABRB1BCL2MCL1LMNA | |
| SCHEMBL8067388 | 0.84 | GABRA1 (0.64) | GABRA1GABRB1BCL2MCL1LMNA | |
| SCHEMBL8077318 | 0.84 | GABRA1 (0.64) | GABRA1GABRB1BCL2MCL1LMNA | |
| SCHEMBL8081926 | 0.84 | GABRA1 (0.64) | GABRA1GABRB1BCL2MCL1LMNA | |
| SCHEMBL8075421 | 0.84 | GABRA1 (0.64) | GABRA1GABRB1BCL2MCL1LMNA | |
| SCHEMBL8075433 | 0.83 | GABRA1 (0.62) | GABRA1GABRB1BCL2MCL1LMNA | |
| SCHEMBL8077077 | 0.81 | GABRA1 (0.60) | GABRA1GABRB1BCL2MCL1LMNA | |
| SCHEMBL8082189 | 0.81 | GABRA1 (0.60) | GABRA1GABRB1BCL2MCL1LMNA | |
| SCHEMBL13639480 | 0.81 | GABRA1 (0.60) | GABRA1GABRB1BCL2MCL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256626-A | 2-BENZIMIDAZOLYL-, 2-BENZOTHIAZOLYL-, OR 2-INDOLYL-PHENYL DERIVATIVES LINKED TO A 2-HYDROXYBENZOPHENONE | EASTMAN KODAK COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
| US-4115348-A | DEGRADATION INHIBITORS | EASTMAN KODAK COMPANY (US) | 1978-09-19 | — | — | US | disclosed |