Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.60 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.60 |
| ▸ | BCL2 | P10415 | 3/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11326985 | 0.81 | GABRA1 (0.68) | GABRA1GABRB1BCL2MCL1GAA | |
| SCHEMBL8077329 | 0.80 | GABRA1 (0.66) | GABRA1GABRB1BCL2MCL1GAA | |
| SCHEMBL11758041 | 0.80 | GABRA1 (0.71) | GABRA1GABRB1BCL2MCL1GAA | |
| SCHEMBL8081926 | 0.79 | GABRA1 (0.64) | GABRA1GABRB1BCL2MCL1GAA | |
| SCHEMBL8067388 | 0.79 | GABRA1 (0.64) | GABRA1GABRB1BCL2MCL1GAA | |
| SCHEMBL8077318 | 0.79 | GABRA1 (0.64) | GABRA1GABRB1BCL2MCL1GAA | |
| SCHEMBL8075421 | 0.79 | GABRA1 (0.64) | GABRA1GABRB1BCL2MCL1GAA | |
| SCHEMBL8075433 | 0.78 | GABRA1 (0.62) | GABRA1GABRB1BCL2MCL1GAA | |
| SCHEMBL8077077 | 0.77 | GABRA1 (0.60) | GABRA1GABRB1BCL2MCL1GAA | |
| SCHEMBL8082189 | 0.77 | GABRA1 (0.60) | GABRA1GABRB1BCL2MCL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520290-A1 | Propofol analogs, process for their preparation, and methods of use | Abraxis BioScience, LLC (US) | 2012-11-07 | — | — | EP | disclosed |