Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 2/20 | 0.62 |
| ▸ | PNMT | P11086 | 5/20 | 0.50 |
| ▸ | PRCP | P42785 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659651 | 0.89 | CD44 (0.72) | CD44PNMTPRCPHTR2CMAOB | |
| SCHEMBL30156803 | 0.89 | CD44 (0.72) | CD44PNMTPRCPHTR2CMAOB | |
| Hydrochloric Acid SCHEMBL4516826 | 0.87 | CD44 (0.70) | CD44PNMTPRCPHTR2CMAOB | |
| SCHEMBL29805405 | 0.78 | CD44 (0.68) | CD44PNMTPRCPMAOBPARP1 | |
| SCHEMBL329619 | 0.78 | CD44 (0.68) | CD44PNMTPRCPMAOBPARP1 | |
| SCHEMBL11327500 | 0.78 | PNMT (0.50) | CD44PNMTPRCPHTR2CMAOB | |
| SCHEMBL11331868 | 0.78 | PNMT (0.79) | CD44PNMTPRCPHTR2CHTR2B | |
| SCHEMBL19684566 | 0.78 | PNMT (0.50) | CD44PNMTPRCPHTR2CMAOB | |
| SCHEMBL11597488 | 0.78 | BCL2L1 (0.60) | CD44PNMTPRCPHTR2C | |
| SCHEMBL14692360 | 0.78 | PNMT (0.50) | CD44PNMTPRCPHTR2CMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002624-B1 | 2-BENZAZEPINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-10-14 | — | — | EP | disclosed |
| EP-0002624-A1 | 2-Benzazepine compounds, processes for their preparation and pharmaceutical compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-06-27 | — | — | EP | disclosed |