SCHEMBL11327883

SCHEMBL11327883

O=[N+]([O-])c1c[nH]c([N+](=O)[O-])c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
GLA P06280 1/20 0.53
CYP19A1 P11511 1/20 0.42
LMNA P02545 4/20 0.41
TSHR P16473 3/20 0.41
CYP3A4 P08684 3/20 0.37
NAMPT P43490 1/20 0.37
XDH P47989 1/20 0.37
MAPT P10636 2/20 0.36
NOS1 P29475 2/20 0.36
ALOX15 P16050 1/20 0.36
POLB P06746 1/20 0.36
MAOB P27338 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
VCAM1 P19320 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8297342 0.76
SCHEMBL31439386 0.74
SCHEMBL9119505 0.74
SCHEMBL827223 0.74
SCHEMBL16423006 0.74
SCHEMBL25434093 0.74
SCHEMBL3293088 0.71 ALDH1A1 (0.63) ALDH1A1GLALMNATSHRCYP3A4
SCHEMBL6214280 0.71 ALDH1A1 (0.48) ALDH1A1GLACYP19A1LMNATSHR
SCHEMBL5409921 0.71 ALDH1A1 (0.48) ALDH1A1GLACYP19A1LMNATSHR
SCHEMBL10562077 0.71 XDH (0.39) ALDH1A1GLACYP19A1CYP3A4XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4300962-A Ammonium nitrate explosive systems THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1981-11-17 US claimed
US-4300962-A Ammonium nitrate explosive systems THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1981-11-17 US disclosed