Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.55 |
| ▸ | PGR | P06401 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726154 | 1.00 | HIF1A (0.55) | HIF1ANR3C1PGRALDH1A1AR | |
| SCHEMBL11328028 | 1.00 | HIF1A (0.55) | HIF1ANR3C1PGRALDH1A1AR | |
| SCHEMBL11726161 | 1.00 | HIF1A (0.55) | HIF1ANR3C1PGRALDH1A1AR | |
| SCHEMBL10427797 | 0.86 | PGR (0.46) | HIF1ANR3C1PGRALDH1A1AR | |
| SCHEMBL10427823 | 0.86 | PGR (0.46) | HIF1ANR3C1PGRALDH1A1AR | |
| SCHEMBL11719344 | 0.85 | HIF1A (0.71) | HIF1ANR3C1PGRALDH1A1AR | |
| SCHEMBL11319052 | 0.85 | HIF1A (0.48) | HIF1ANR3C1PGRALDH1A1AR | |
| SCHEMBL11319047 | 0.85 | HIF1A (0.48) | HIF1ANR3C1PGRALDH1A1AR | |
| SCHEMBL11400580 | 0.85 | HIF1A (0.71) | HIF1ANR3C1PGRALDH1A1AR | |
| SCHEMBL11719352 | 0.85 | HIF1A (0.71) | HIF1ANR3C1PGRALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255331-A | 3-Acetoxy-9β-11β-epoxy-dienes and the preparation of the corresponding 6α-halogen-4-ene-3-ones | PROCHEM ESTABLISHMENT (LI) | 1981-03-10 | — | — | US | disclosed |