Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 6/20 | 0.46 |
| ▸ | AR | P10275 | 6/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11319047 | 1.00 | HIF1A (0.48) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL11726161 | 0.85 | HIF1A (0.55) | HIF1ALMNAPGRARCHRM1 | |
| SCHEMBL11328028 | 0.85 | HIF1A (0.55) | HIF1ALMNAPGRARCHRM1 | |
| SCHEMBL11726154 | 0.85 | HIF1A (0.55) | HIF1ALMNAPGRARCHRM1 | |
| SCHEMBL11328032 | 0.85 | HIF1A (0.55) | HIF1ALMNAPGRARCHRM1 | |
| SCHEMBL5708002 | 0.84 | HIF1A (0.63) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL10937267 | 0.84 | HIF1A (0.63) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL11362338 | 0.84 | HIF1A (0.63) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL32668997 | 0.84 | HIF1A (0.63) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL11312288 | 0.82 | HIF1A (0.59) | HIF1ALMNANPSR1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255331-A | 3-Acetoxy-9β-11β-epoxy-dienes and the preparation of the corresponding 6α-halogen-4-ene-3-ones | PROCHEM ESTABLISHMENT (LI) | 1981-03-10 | — | — | US | disclosed |