Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PTGIR | P43119 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.42 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11328407 | 0.85 | ALOX5 (0.42) | SMN1; SMN2ALOX5CFTRHPGDALDH1A1 | |
| SCHEMBL11326646 | 0.85 | PTGIR (0.55) | SMN1; SMN2PTGIRALOX5HPGDGAA | |
| SCHEMBL11118484 | 0.83 | CFTR (0.43) | SMN1; SMN2PTGIRCFTRALDH1A1CYP3A4 | |
| SCHEMBL11338014 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2ALOX5CFTRHPGDALDH1A1 | |
| SCHEMBL11340956 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2ALOX5CFTRHPGDALDH1A1 | |
| SCHEMBL11194621 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2ALOX5GAAADRA2CALDH1A1 | |
| SCHEMBL11310893 | 0.79 | MAPT (0.42) | SMN1; SMN2PTGIRCFTRALDH1A1MAPT | |
| SCHEMBL11317245 | 0.78 | PTGIR (0.42) | SMN1; SMN2PTGIRALOX5ALDH1A1CYP3A4 | |
| SCHEMBL11327162 | 0.78 | CFTR (0.43) | SMN1; SMN2ALOX5CFTRNPSR1 | |
| SCHEMBL11317140 | 0.78 | CFTR (0.43) | SMN1; SMN2ALOX5CFTRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243678-A | GASTROINTESTINAL DISORDERS, LIVER DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-01-06 | — | — | US | disclosed |