Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340956 | 0.99 | SMN1; SMN2 (0.41) | SMN1; SMN2CFTRCYP4F2CYP4A11ALOX5 | |
| SCHEMBL11328407 | 0.98 | ALOX5 (0.42) | SMN1; SMN2CFTRCYP4F2CYP4A11ALOX5 | |
| SCHEMBL11326634 | 0.87 | ALOX5 (0.42) | SMN1; SMN2CYP4F2CYP4A11ALOX5S1PR1 | |
| SCHEMBL11289885 | 0.85 | ALDH1A1 (0.43) | SMN1; SMN2S1PR1NPSR1ALDH1A1CYP3A4 | |
| SCHEMBL11295980 | 0.84 | ALDH1A1 (0.42) | SMN1; SMN2S1PR1NPSR1ALDH1A1CYP3A4 | |
| SCHEMBL11335525 | 0.83 | MEN1 (0.56) | SMN1; SMN2CYP4F2CYP4A11PTPN1PPARG | |
| SCHEMBL11322643 | 0.83 | ALDH1A1 (0.43) | SMN1; SMN2S1PR1PPARGNPSR1ALDH1A1 | |
| SCHEMBL11294522 | 0.83 | CFTR (0.44) | SMN1; SMN2CFTRCYP4F2CYP4A11ALOX5 | |
| SCHEMBL11328131 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2CFTRALOX5NPSR1ALDH1A1 | |
| SCHEMBL11328985 | 0.82 | MEN1 (0.57) | SMN1; SMN2ALOX5PTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243678-A | GASTROINTESTINAL DISORDERS, LIVER DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-01-06 | — | — | US | disclosed |