Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332350 | 0.88 | MAPT (0.57) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL11332351 | 0.88 | MAPT (0.57) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL11337898 | 0.84 | MAPT (0.74) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL9359757 | 0.80 | MAPT (0.85) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL11341691 | 0.80 | MAPT (0.85) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL3372495 | 0.80 | MAPT (1.00) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL5045089 | 0.78 | MEN1 (0.57) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL5042031 | 0.77 | MAPT (0.51) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL11334630 | 0.77 | MAPT (0.70) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL11329121 | 0.76 | MAPT (0.70) | MAPTRAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4265804-A | BENZOXAZOYLBENZOATES, OXADIAZOLE-2,5-DIBENZOATES, BENZOTRIAZOLES AND BENZOTRIAZOTRIAZOLES | EASTMAN KODAK COMPANY (US) | 1981-05-05 | — | — | US | disclosed |