Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.85 |
| ▸ | RAB9A | P51151 | 7/20 | 0.85 |
| ▸ | NPC1 | O15118 | 6/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.85 |
| ▸ | HPGD | P15428 | 4/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.85 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341691 | 1.00 | MAPT (0.85) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL3372495 | 0.92 | MAPT (1.00) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL17565788 | 0.86 | MAPT (0.70) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL4826178 | 0.85 | RAB9A (0.66) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL4826174 | 0.85 | RAB9A (0.66) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL1258969 | 0.85 | SMN1; SMN2 (0.71) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL9767559 | 0.85 | SMN1; SMN2 (0.71) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL8155474 | 0.85 | NPC1 (0.60) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL6707325 | 0.84 | SMN1; SMN2 (0.69) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL19690361 | 0.83 | NPC1 (0.67) | MAPTRAB9ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385890-B1 | Pocess for the preparation of stilbene derivatives | EASTMAN CHEM CO (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0472525-A1 | PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES | EASTMAN KODAK COMPANY (US) | 1992-03-04 | — | — | EP | disclosed |
| WO-1990010001-A1 | PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES | EASTMAN KODAK COMPANY (US) | 1990-09-07 | — | — | WO | disclosed |
| EP-0385890-A1 | Pocess for the preparation of stilbene derivatives | EASTMAN CHEMICAL COMPANY (US) | 1990-09-05 | — | — | EP | disclosed |
| US-4921964-A | Process for the preparation of stilbene derivatives | EASTMAN KODAK COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4304569-A | Formulation for brightening synthetic fibers and its preparation and use | CASSELLA AG. (DE) | 1981-12-08 | — | — | US | disclosed |
| EP-0029972-A2 | Preparation for brightening synthetic fibres, process for its preparation and process for optical brightening | CASSELLA Aktiengesellschaft (DE) | 1981-06-10 | — | — | EP | disclosed |