SCHEMBL11328348

SCHEMBL11328348

C=CCCCCCCCCS(=O)(=O)c1ccc(C(C)=O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
ALDH1A1 P00352 6/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 2/20 0.40
CA2 P00918 3/20 0.40
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
GAA P10253 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11329395 0.85 CA2 (0.45) THRATHRBALDH1A1CYP3A4CYP2C9
SCHEMBL11333859 0.85 ALDH1A1 (0.53) THRATHRBALDH1A1CYP3A4CYP2C9
SCHEMBL19392446 0.85 ALDH1A1 (0.40) THRATHRBALDH1A1CYP3A4CYP2C9
SCHEMBL8834888 0.81 ALDH1A1 (0.65) ALDH1A1CYP3A4CYP2C9CYP2C19CA2
SCHEMBL8834639 0.81 ALDH1A1 (0.65) ALDH1A1CYP3A4CYP2C9CYP2C19CA2
SCHEMBL8835388 0.81 ALDH1A1 (0.65) ALDH1A1CYP3A4CYP2C9CYP2C19CA2
SCHEMBL8834960 0.81 ALDH1A1 (0.65) ALDH1A1CYP3A4CYP2C9CYP2C19CA2
SCHEMBL8834611 0.81 ALDH1A1 (0.65) ALDH1A1CYP3A4CYP2C9CYP2C19CA2
SCHEMBL8834905 0.81 ALDH1A1 (0.65) ALDH1A1CYP3A4CYP2C9CYP2C19CA2
SCHEMBL9299607 0.81 ALDH1A1 (0.65) ALDH1A1CYP3A4CYP2C9CYP2C19CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4260552-A INSECTICIDES, HERBICIDES UNIROYAL, INC. (US) 1981-04-07 US disclosed
US-4160846-A Method for controlling insects with tetrasubstituted organotin compounds UNIROYAL, INC. (US) 1979-07-10 US disclosed