Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | AR | P10275 | 3/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11328354 | 1.00 | HIF1A (0.61) | HIF1ANR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL11331377 | 0.94 | CYP3A4 (0.63) | HIF1ANR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL11331386 | 0.94 | CYP3A4 (0.63) | HIF1ANR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL11491230 | 0.93 | ABCB11 (0.61) | HIF1ANR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL11491227 | 0.93 | ABCB11 (0.61) | HIF1ANR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL11482607 | 0.93 | CYP3A4 (0.55) | HIF1ANR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL11482600 | 0.93 | CYP3A4 (0.55) | HIF1ANR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL11331836 | 0.91 | HIF1A (0.63) | HIF1ANR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL11331846 | 0.91 | HIF1A (0.63) | HIF1ANR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL11286872 | 0.91 | NR3C1 (0.56) | HIF1ANR3C1CYP3A4ABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243664-A | 17,21-DIACYLOXY-11-FLUORO-1,4,8-PREGNATRIENE-3,20-DIONES, ANTIINFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |
| US-4176126-A | ANTIINFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-11-27 | — | — | US | disclosed |