Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCLC | P48506 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338551 | 0.89 | GCLC (0.41) | GCLCCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL11339295 | 0.84 | FDPS (0.34) | GCLCCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL11339923 | 0.81 | FDPS (0.38) | GCLCCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL8843030 | 0.80 | CHRM1 (0.35) | GCLCCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL11342329 | 0.78 | CHRM1 (0.47) | GCLCCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL11344898 | 0.77 | GRM3 (0.38) | HDAC1HDAC2GRM3MEN1KMT2A | |
| SCHEMBL11331390 | 0.72 | GCLC (0.30) | GCLC | |
| SCHEMBL27837595 | 0.69 | HSPD1 (0.42) | HDAC1HDAC2CA2MAPK1GRM3 | |
| SCHEMBL11510608 | 0.68 | CHRM1 (0.36) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL11334407 | 0.68 | METAP1 (0.39) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252857-A | Flameproofing substrate | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |
| US-4133872-A | Compositions for preparation of aqueous solutions of salts of lower valence 99 technetium | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1979-01-09 | — | — | US | disclosed |
| US-4086334-A | A CALCITONIN AND AN ADJUVANT CONTAINING CARBOXY AND/OR PHOSPHONO GROUPS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DT) | 1978-04-25 | — | — | US | disclosed |
| US-3962433-A | Method of treatment of calcium disorders using phosphonoalkane-polycarboxylic acids | HENKEL & CIE G.M.B.H. (DT) | 1976-06-08 | — | — | US | disclosed |