Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.68 |
| ▸ | CA1 | P00915 | 7/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13893214 | 0.81 | CA1 (0.72) | CA2CA1 | |
| SCHEMBL10626668 | 0.81 | CA2 (0.68) | CA2CA1PTPN1MAPK1SMN1; SMN2 | |
| SCHEMBL7525890 | 0.81 | CA2 (0.68) | CA2CA1PTPN1MAPK1SMN1; SMN2 | |
| SCHEMBL3155581 | 0.80 | PTPN1 (0.63) | CA2CA1PTPN1MAPK1SMN1; SMN2 | |
| SCHEMBL10623902 | 0.78 | CA2 (0.66) | CA2CA1PTPN1MAPK1SMN1; SMN2 | |
| SCHEMBL7527132 | 0.78 | PTPN1 (0.66) | CA2CA1PTPN1MAPK1SMN1; SMN2 | |
| SCHEMBL7524156 | 0.76 | PTPN1 (0.63) | CA2CA1PTPN1MAPK1SMN1; SMN2 | |
| SCHEMBL6881190 | 0.76 | PTPN1 (0.63) | CA2CA1PTPN1MAPK1SMN1; SMN2 | |
| SCHEMBL4049597 | 0.76 | CA2 (0.67) | CA2CA1PTPN1MAPK1SMN1; SMN2 | |
| SCHEMBL11121097 | 0.76 | PTPN11 (0.72) | CA2CA1PTPN1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288592-A | Process for preparing amides by reaction in presence of molecular sieve | AMERICAN CYANAMID COMPANY (US) | 1981-09-08 | — | — | US | disclosed |