SCHEMBL10623902

SCHEMBL10623902

CNS(=O)(=O)c1ccc(NS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.66
CA1 P00915 6/20 0.66
PTPN11 Q06124 1/20 0.59
PTPN1 P18031 1/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
MAPK1 P28482 2/20 0.56
ALDH1A1 P00352 4/20 0.54
GAA P10253 1/20 0.50
CA12 O43570 1/20 0.48
CA3 P07451 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA13 Q8N1Q1 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7525890 0.81 CA2 (0.68) CA2CA1PTPN11PTPN1SMN1; SMN2
SCHEMBL13690232 0.81 PTPN11 (0.67) CA2CA1PTPN11PTPN1SMN1; SMN2
SCHEMBL13034867 0.78 ALDH1A1 (0.50) CA2CA1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL10626668 0.78 CA2 (0.68) CA2CA1PTPN11PTPN1SMN1; SMN2
SCHEMBL11328699 0.78 CA2 (0.68) CA2CA1PTPN11PTPN1SMN1; SMN2
SCHEMBL17774980 0.77 PTPN11 (0.67) CA2CA1PTPN11PTPN1SMN1; SMN2
SCHEMBL7629070 0.76 SMN1; SMN2 (0.80) CA2CA1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL7527132 0.75 PTPN1 (0.66) CA2CA1PTPN11PTPN1SMN1; SMN2
SCHEMBL13110661 0.74 SMN1; SMN2 (0.64) CA2CA1SMN1; SMN2ALDH1A1GAA
SCHEMBL10587934 0.74 PTPN1 (0.59) CA2CA1PTPN11PTPN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58126858-A None JP disclosed
JP-58188852-A None JP disclosed
US-4767446-A PREEMERGENCE OR POSTEMERGENCE HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-30 US disclosed
US-4564386-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-01-14 US disclosed
EP-0072253-B1 TRIFLUOROMETHANESULFONANILIDES, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-11-13 EP disclosed
JP-S58188852-A TRIFLUOROMETHANESULFONANILIDE DERIVATIVE, ITS PREPARATION, AND INSECTICIDE CONTAINING IT AS ACTIVE INGREDIENT SUMITOMO CHEM CO LTD 1983-11-04 JP disclosed
JP-S58126858-A TRIFLUOROMETHANESULFONEANILIDE DERIVATIVE, ITS PREPARATION, AND HERBICIDE CONTAINING IT AS ACTIVE INGREDIENT SUMITOMO CHEM CO LTD 1983-07-28 JP disclosed
EP-0072253-A2 Trifluoromethanesulfonanilides, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-02-16 EP disclosed