SCHEMBL11329263

SCHEMBL11329263

C=Cc1nccnc1CC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDXK O00764 1/20 0.31
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3931270 0.77 PDE3B (0.34) PDE3BPDE3A
SCHEMBL29954185 0.77 PDE3B (0.34) PDE3BPDE3A
SCHEMBL19957888 0.76 PDE3B (0.30) PDE3BPDE3A
SCHEMBL18773548 0.76 PDE3B (0.30) PDE3BPDE3A
SCHEMBL873036 0.74 HDAC8 (0.32) PDXK
SCHEMBL1131513 0.74 PDE3B (0.39) PDE3BPDE3A
SCHEMBL32659903 0.74 HDAC8 (0.32) PDXK
SCHEMBL34472956 0.74 PDE3B (0.39) PDE3BPDE3A
SCHEMBL11213548 0.73 PDE3B (0.31) PDE3BPDE3A
SCHEMBL3922347 0.72 FGF23 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140127326-A1 Detection of Cancer by Volatile Organic Compounds From Breath BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2014-05-08 US claimed
WO-2012122128-A2 DETECTION OF CANCER BY VOLATILE ORGANIC COMPOUNDS FROM BREATH BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-09-13 WO claimed
CN-107057830-B A kind of method of near-infrared pretreatment auxiliary aqueous enzymatic extraction rapeseed oil 江南大学 2019-09-03 CN disclosed
EP-3208272-A1 HETEROCYCLIC MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS Vertex Pharmaceuticals Incorporated (US) 2017-08-23 EP disclosed
CN-107057830-A A kind of method of near-infrared pretreatment auxiliary aqueous enzymatic extraction rapeseed oil 江南大学 2017-08-18 CN disclosed
US-20140127326-A1 Detection of Cancer by Volatile Organic Compounds From Breath BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2014-05-08 US disclosed
WO-2012122128-A2 DETECTION OF CANCER BY VOLATILE ORGANIC COMPOUNDS FROM BREATH BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-09-13 WO disclosed
WO-2012122128-A2 DETECTION OF CANCER BY VOLATILE ORGANIC COMPOUNDS FROM BREATH BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-09-13 WO disclosed
US-4303689-A Flavoring with pyrazine derivatives FIRMENICH SA (CH) 1981-12-01 US disclosed
US-4138410-A Flavoring agent FIRMENICH & CIE (CH) 1979-02-06 US disclosed
US-4126618-A FLAVOR ADDITIVES FOR FOODS AND BEVERAGES FIRMENICH & CIE (CH) 1978-11-21 US disclosed
US-4085109-A Pyridine sulfur flavoring agents FIRMENICH & CIE (CH) 1978-04-18 US disclosed
US-3989713-A Pyrrylmethylthio flavoring agents FIRMENICH & CIE (CH) 1976-11-02 US disclosed
US-3952026-A FLAVOR ADDITIVE FOR FOODS AND BEVERAGES FIRMENICH & CIE (CH) 1976-04-20 US disclosed
US-3952024-A FLAVOR ADDITIVE FOR FOODS AND BEVERAGES FIRMENICH & CIE (CH) 1976-04-20 US disclosed
US-3943260-A TETRAHYDRO-THIO-PHEN-3-ONES FIRMENICH & CIE (CH) 1976-03-09 US disclosed
US-3931166-A FLAVORANTS FIRMENICH & CIE (CH) 1976-01-06 US disclosed
US-3931246-A FURYLALKYL-THIOETHERS FIRMENICH & CIE (CH) 1976-01-06 US disclosed
US-3931245-A FURYLALKYLTHIOL CARBOXYLATES FIRMENICH & CIE (CH) 1976-01-06 US disclosed