SCHEMBL11213548

SCHEMBL11213548

C=CCc1nccnc1CC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1465555 0.88 CCNB2 (0.30)
SCHEMBL34472956 0.80 PDE3B (0.39) PDE3BPDE3A
SCHEMBL1131513 0.80 PDE3B (0.39) PDE3BPDE3A
SCHEMBL6449401 0.79 PDE3B (0.35) PDE3BPDE3A
SCHEMBL28323729 0.77 PDXK (0.32)
Ammonia Solution, Strong SCHEMBL28980458 0.77 PDE3B (0.38) PDE3BPDE3A
SCHEMBL4686333 0.73 PDE3B (0.33) PDE3BPDE3A
SCHEMBL11329263 0.73 PDXK (0.31) PDE3BPDE3A
SCHEMBL4564372 0.73 XDH (0.33)
SCHEMBL11788495 0.73 FFAR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0076085-A1 Production of monoacylpyrazines PHILIP MORRIS INCORPORATED (US) 1983-04-06 EP disclosed