Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MTOR | P42345 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317980 | 1.00 | ADORA2A (0.55) | ADORA2AADORA3ADORA2BADORA1LMNA | |
| SCHEMBL11317987 | 1.00 | ADORA2A (0.55) | ADORA2AADORA3ADORA2BADORA1LMNA | |
| SCHEMBL11313276 | 0.94 | ADORA3 (0.56) | ADORA2AADORA3ADORA2BADORA1LMNA | |
| SCHEMBL11313270 | 0.94 | ADORA3 (0.56) | ADORA2AADORA3ADORA2BADORA1LMNA | |
| SCHEMBL11315837 | 0.94 | ADORA3 (0.56) | ADORA2AADORA3ADORA2BADORA1LMNA | |
| SCHEMBL2578281 | 0.89 | LMNA (0.57) | ADORA2AADORA3ADORA2BADORA1LMNA | |
| SCHEMBL11316762 | 0.88 | LMNA (0.56) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL11325017 | 0.88 | LMNA (0.56) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL11316774 | 0.88 | LMNA (0.56) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL11665906 | 0.86 | LMNA (0.54) | ADORA2AADORA2BLMNAMTORTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267171-A | C-5 Substituted cytosine nucleosides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1981-05-12 | — | — | US | disclosed |