Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330792 | 0.94 | GBA1 (0.38) | GBA1ALDH1A1KDM4EMEN1PABPC1 | |
| SCHEMBL11367947 | 0.87 | GBA1 (0.41) | GBA1ALDH1A1KDM4EMEN1RGS12 | |
| SCHEMBL11328124 | 0.85 | L3MBTL1 (0.34) | GBA1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL11317793 | 0.80 | GBA1 (0.53) | GBA1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10458192 | 0.78 | L3MBTL1 (0.38) | GBA1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL11360026 | 0.78 | GBA1 (0.40) | GBA1ALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL11364597 | 0.76 | GBA1 (0.38) | GBA1ALDH1A1MEN1HTTKMT2A | |
| SCHEMBL11359259 | 0.73 | GBA1 (0.70) | GBA1ALDH1A1KDM4ETP53GAA | |
| SCHEMBL11399389 | 0.72 | PTGS1 (0.47) | GBA1MEN1LMNAKMT2AGAA | |
| SCHEMBL11383758 | 0.71 | GBA1 (0.40) | GBA1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042478-A1 | Method for the adhesion of rubber to reinforcing materials | AMERICAN CYANAMID COMPANY (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4306872-A | Imidazolidinones in a durable press process | AMERICAN CYANAMID COMPANY (US) | 1981-12-22 | — | — | US | disclosed |
| US-4300973-A | ADDING AN IMIDAZOLIDINONE | AMERICAN CYANAMID COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| US-4284536-A | IMIDAZOLIDINONE ADDITIVE | AMERICAN CYANAMID CO. (US) | 1981-08-18 | — | — | US | disclosed |