SCHEMBL11328124

SCHEMBL11328124

O=C1N(CCO)C(O)C(O)N1CN1C(=O)N(CN2C(=O)N(CCO)C(O)C2O)C(O)C1O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.34
GBA1 P04062 1/20 0.32
KMT2A Q03164 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10458192 0.93 L3MBTL1 (0.38) L3MBTL1GBA1KMT2AKDM4E
SCHEMBL11330792 0.87 GBA1 (0.38) L3MBTL1GBA1KMT2AKDM4E
SCHEMBL11329338 0.85 GBA1 (0.41) L3MBTL1GBA1KMT2AKDM4E
SCHEMBL9972944 0.83 L3MBTL1 (0.50) L3MBTL1GBA1KDM4E
SCHEMBL11367947 0.79 GBA1 (0.41) L3MBTL1GBA1KMT2AKDM4E
SCHEMBL11317793 0.77 GBA1 (0.53) L3MBTL1GBA1KMT2A
SCHEMBL18106281 0.75 L3MBTL1 (0.50) L3MBTL1GBA1KMT2AKDM4E
SCHEMBL11365531 0.75 GBA1 (0.33) L3MBTL1GBA1
SCHEMBL11360561 0.75 ALDH1A1 (0.36) L3MBTL1GBA1KMT2AKDM4E
SCHEMBL11366729 0.75 ALDH1A1 (0.36) L3MBTL1GBA1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4306872-A Imidazolidinones in a durable press process AMERICAN CYANAMID COMPANY (US) 1981-12-22 US disclosed
US-4300973-A ADDING AN IMIDAZOLIDINONE AMERICAN CYANAMID COMPANY (US) 1981-11-17 US disclosed
US-4284536-A IMIDAZOLIDINONE ADDITIVE AMERICAN CYANAMID CO. (US) 1981-08-18 US disclosed