Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12671895 | 0.85 | SMN1; SMN2 (0.57) | GAAMAPTPOLBACP3SMN1; SMN2 | |
| SCHEMBL17078082 | 0.85 | SMN1; SMN2 (0.57) | GAAMAPTPOLBACP3SMN1; SMN2 | |
| SCHEMBL12671909 | 0.85 | SMN1; SMN2 (0.57) | GAAMAPTPOLBACP3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2528761 | 0.83 | SMN1; SMN2 (0.55) | GAAMAPTPOLBACP3SMN1; SMN2 | |
| SCHEMBL8705659 | 0.83 | GGT1 (0.50) | POLBACESMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL29924046 | 0.81 | FOLH1 (0.47) | GAAMAPTPOLBADH1BADH1C | |
| SCHEMBL8903656 | 0.80 | ALDH1A1 (0.34) | ADH1BADH1CADH1AADH7ACP3 | |
| SCHEMBL11581853 | 0.80 | MME (0.56) | ALDH1A1FOLH1 | |
| SCHEMBL1190016 | 0.80 | PDCD1 (0.53) | GAAMAPTPOLBACP3ALDH1A1 | |
| SCHEMBL1190014 | 0.80 | PDCD1 (0.53) | GAAMAPTPOLBACP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101889011-B | Derivatives of 6,7-dihydro-5h-imidazo[1,2-a]imidazole-3- carboxylic acid amides | BOEHRINGER INGELHEIM INT | 2014-05-28 | — | — | CN | disclosed |
| CN-101889011-A | Derivatives of 6,7-dihydro-5h-imidazo[1,2-a]imidazole-3- carboxylic acid amides | BOEHRINGER INGELHEIM INT | 2010-11-17 | — | — | CN | disclosed |
| US-4293543-A | ALDEHYDES OR KETONES AND SULFOXYAMINO ACIDS | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1981-10-06 | — | — | US | disclosed |