Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.78 |
| ▸ | DRD2 | P14416 | 6/20 | 0.78 |
| ▸ | HTR2A | P28223 | 4/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HTR6 | P50406 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11318644 | 1.00 | HTR1A (0.78) | HTR1ADRD2HTR2AHTTSIGMAR1 | |
| SCHEMBL7543848 | 0.88 | HTR1A (1.00) | HTR1ADRD2HTR2AHTTSIGMAR1 | |
| SCHEMBL10677156 | 0.86 | HTR1A (0.59) | HTR1ADRD2HTR2AHTTSIGMAR1 | |
| SCHEMBL11223590 | 0.85 | KDM4E (0.73) | HTR1ADRD2HTR2AHTTSIGMAR1 | |
| SCHEMBL4482017 | 0.85 | KDM4E (0.73) | HTR1ADRD2HTR2AHTTSIGMAR1 | |
| Hydrochloric Acid SCHEMBL11313113 | 0.85 | KDM4E (0.81) | HTR1ADRD2HTR2AHTTSIGMAR1 | |
| SCHEMBL11315106 | 0.85 | KDM4E (0.81) | HTR1ADRD2HTR2AHTTSIGMAR1 | |
| SCHEMBL7527363 | 0.84 | SLC6A4 (0.66) | HTR1ADRD2HTR2AHTTSIGMAR1 | |
| SCHEMBL9467235 | 0.83 | SIGMAR1 (1.00) | HTR1ADRD2HTR2AHTTSIGMAR1 | |
| SCHEMBL4491839 | 0.83 | KDM4E (0.70) | HTR1ADRD2HTR2AHTTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4278677-A | Tetrahydropyridinyl indoles | ROUSSEL UCLAF (FR) | 1981-07-14 | — | — | US | disclosed |