SCHEMBL1133003

SCHEMBL1133003

O=C1COC2(CCCCC2)O1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.34
POLB P06746 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 5/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8631677 0.77 POLB (0.39) TDP1POLBALDH1A1
SCHEMBL15156765 0.75 KDM4E (0.31) ALDH1A1KDM4EMAPT
SCHEMBL15157202 0.75 KDM4E (0.31) ALDH1A1KDM4EMAPT
SCHEMBL2581832 0.74 SMN1; SMN2 (0.38) TDP1SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL14021448 0.74 SMN1; SMN2 (0.38) TDP1SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL5708919 0.74 SMN1; SMN2 (0.38) TDP1SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL16169953 0.74 POLB (0.41) TDP1POLBSMN1; SMN2
SCHEMBL7887353 0.73
SCHEMBL5708888 0.70 SMN1; SMN2 (0.39) TDP1POLBSMN1; SMN2ALDH1A1KDM4E
SCHEMBL18101503 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8877349-B2 Organometallic complex and organic electroluminescence device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-04 US claimed
US-8039123-B2 Phosphorescent heteronuclear copper(I)-iridium(III) complex and organic electroluminescence device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-10-18 US claimed
EP-1874132-A1 HOT FLAVOUR AND SKIN SENSATION COMPOSITION FIRMENICH SA (CH) 2008-01-09 EP claimed
US-20070267959-A1 Phosphorescent heteronuclear copper(I)-iridium(III) complex and organic electroluminescence device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-11-22 US claimed
US-7294415-B2 Organometallic complex and organic electroluminescent device employing the same SAMSUNG SDI CO., LTD. (KR) 2007-11-13 US claimed
US-20070178332-A1 highly efficient phosphorescent organometallic complex and an organic electroluminescent (EL) device using the same. The organometallic complex can be used in the formation of an organic layer of the organic EL device, and can emit red light from phosphorescent material SAMSUNG DISPLAY CO., LTD. (KR) 2007-08-02 US claimed
WO-2006109241-A1 HOT FLAVOUR AND SKIN SENSATION COMPOSITION FIRMENICH SA (CH) 2006-10-19 WO claimed
US-20040265633-A1 Organometallic complex and organic electroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2004-12-30 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
EP-3643735-B1 PHOTOCHROMIC POLYROTAXANE COMPOUND, AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC POLYROTAXANE COMPOUND TOKUYAMA CORP (JP) 2024-07-31 EP disclosed
EP-3498742-B1 PHOTOCHROMIC CURABLE COMPOSITION, USE THEREOF, AND POLYROTAXANE MONOMERS TOKUYAMA CORP (JP) 2024-06-12 EP disclosed
US-20240101751-A1 HOLLOW MICROBALLOON TOKUYAMA CORPORATION (JP) 2024-03-28 US disclosed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US disclosed
EP-0207773-A2 7-[(Substituted)amino]-8-[(substituted)carbonyl)-methylamino]-1-oxaspiro[4.5]decanes as analgesic agents WARNER-LAMBERT COMPANY (US) 1987-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070267959-A1 Phosphorescent heteronuclear copper(I)-iridium(III) complex and organic electroluminescence device using the same ORC3, AP3M1, PUF60 TDP1 2901/4885POLB 834/4885SMN1; SMN2 2630/4885
US-20040265633-A1 Organometallic complex and organic electroluminescent device employing the same TYR, CYBA, LAGE3 TDP1 4281/4885POLB 2744/4885SMN1; SMN2 4492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.