SCHEMBL2581832

SCHEMBL2581832

O=C1CC(=O)OC2(CCCCC2)O1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
PTPN1 P18031 1/20 0.38
ACP1 P24666 1/20 0.38
CDC25B P30305 1/20 0.38
ALDH1A1 P00352 12/20 0.38
KDM4E B2RXH2 4/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
PKM P14618 2/20 0.34
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
LMNA P02545 2/20 0.34
RECQL P46063 1/20 0.34
MAPK1 P28482 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14021448 1.00 SMN1; SMN2 (0.38) SMN1; SMN2PTPN1ACP1CDC25BALDH1A1
SCHEMBL5708919 1.00 SMN1; SMN2 (0.38) SMN1; SMN2PTPN1ACP1CDC25BALDH1A1
SCHEMBL5708888 0.97 SMN1; SMN2 (0.39) SMN1; SMN2PTPN1ACP1CDC25BALDH1A1
SCHEMBL17064148 0.92 SMN1; SMN2 (0.35) SMN1; SMN2PTPN1ACP1CDC25BALDH1A1
SCHEMBL21081502 0.88 PTPN1 (0.32) SMN1; SMN2PTPN1ACP1CDC25BALDH1A1
SCHEMBL9889189 0.88 PTPN1 (0.32) SMN1; SMN2PTPN1ACP1CDC25BALDH1A1
SCHEMBL14372437 0.84 SMN1; SMN2 (0.37) SMN1; SMN2PTPN1ACP1CDC25BALDH1A1
SCHEMBL17072788 0.84 PTPN1 (0.33) SMN1; SMN2PTPN1ACP1CDC25BALDH1A1
SCHEMBL13203925 0.77 LMNA (0.34) SMN1; SMN2ALDH1A1LMNATSHR
SCHEMBL5708918 0.77 CYP1A2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683914-A2 RADIOLABELED FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND METHODS OF MAKING SAME Regents of the University of Michigan (US) 2026-01-28 EP claimed
EP-3830160-B1 METHODS FOR REDUCING ALDEHYDE EMISSIONS IN POLYURETHANE FOAMS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-06-25 EP claimed
WO-2024197111-A2 RADIOLABELED FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND METHODS OF MAKING SAME REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-09-26 WO claimed
CN-112638975-B Method for reducing aldehyde emissions in polyurethane foams 陶氏环球技术有限责任公司 2023-05-16 CN claimed
CN-112585184-B Method for reducing aldehyde emissions in polyurethane foams 陶氏环球技术有限责任公司 2023-04-11 CN claimed
US-11479650-B2 Methods for reducing aldehyde emissions in polyurethane foams DOW GLOBAL TECHNOLOGIES LLC (US) 2022-10-25 US claimed
CN-110446731-B Polyurethane foams with low aldehyde emission levels 陶氏环球技术有限责任公司 2022-06-07 CN claimed
US-20210292508-A1 METHODS FOR REDUCING ALDEHYDE EMISSIONS IN POLYURETHANE FOAMS DOW CHEMICAL JAPAN LIMITED (JP) 2021-09-23 US claimed
US-20210189054-A1 METHODS FOR REDUCING ALDEHYDE EMISSIONS IN POLYURETHANE FOAMS DOW GLOBAL TECHNOLOGIES LLC 2021-06-24 US claimed
CN-112638975-A Method for reducing aldehyde emissions in polyurethane foams 陶氏环球技术有限责任公司 2021-04-09 CN claimed
CN-112585184-A Method for reducing aldehyde emissions in polyurethane foams 陶氏环球技术有限责任公司 2021-03-30 CN claimed
US-20200031983-A1 POLYURETHANES HAVING LOW LEVELS OF ALDEHYDE EMISSIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-01-30 US claimed
US-20160075678-A1 FACILE AND SELECTIVE PERFLUORO-AND POLYFLUOROARYLATION OF MELDRUMS ACID THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY 2016-03-17 US claimed
WO-2015080675-A1 MOLECULAR WEIGHT ENHANCING AGENT OF POLYESTER COMPRISING AMIDOALKYLIDENE MALONATE, A PROCESS OF ENHANCING MOLECULAR WEIGHT AND POLYESTER OBTAINED FROM SAID MOLECULAR WEIGHT ENHANCING AGENT PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2015-06-04 WO claimed
EP-1433469-B1 Composition for dyeing keratinous fibres HENKEL KGAA (DE) 2006-10-11 EP claimed
EP-1433469-A1 Composition for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
EP-4683914-A2 RADIOLABELED FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND METHODS OF MAKING SAME Regents of the University of Michigan (US) 2026-01-28 EP disclosed
EP-3830160-B1 METHODS FOR REDUCING ALDEHYDE EMISSIONS IN POLYURETHANE FOAMS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-06-25 EP disclosed
US-4418142-A ALDEHYDE SCAVANGERS AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1983-11-29 US disclosed
US-4163116-A REACTING A PHENOL AND AN ESTER CONTAINING COMPOUND GENERAL ELECTRIC COMPANY (US) 1979-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160075678-A1 FACILE AND SELECTIVE PERFLUORO-AND POLYFLUOROARYLATION OF MELDRUMS ACID FXR2, ALAD, FXR1 SMN1; SMN2 1942/4885PTPN1 3797/4885ACP1 3642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.