Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24435805 | 0.82 | MCL1 (0.60) | CA2PTGS1PTGS2MCL1HPGD | |
| SCHEMBL4976180 | 0.82 | PTGS1 (0.73) | CA2PTGS1PTGS2HPGDCA1 | |
| SCHEMBL10626660 | 0.81 | CA2 (0.75) | CA2PTGS1PTGS2CA1PDK1 | |
| SCHEMBL2079574 | 0.80 | CA2 (0.49) | CA2PTGS1PTGS2CA1 | |
| SCHEMBL4303918 | 0.79 | CA2 (0.60) | CA2PTGS1PTGS2MCL1CA1 | |
| SCHEMBL6001650 | 0.79 | PTGS1 (0.67) | CA2PTGS1PTGS2 | |
| SCHEMBL10934176 | 0.78 | PTGS1 (0.64) | CA2PTGS1PTGS2MCL1TSHR | |
| SCHEMBL2080327 | 0.78 | CA2 (0.47) | CA2PTGS1PTGS2CA1 | |
| SCHEMBL6000979 | 0.78 | CA2 (0.51) | CA2PTGS1PTGS2MCL1HPGD | |
| SCHEMBL4968060 | 0.77 | PTGS1 (0.50) | CA2PTGS1PTGS2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010844-B1 | NOVEL N,N'-BIS(TRIFLUOROMETHYLSULFONYL)OXAMIDES, CHEMILUMINESCENT COMPOSITIONS CONTAINING THEM AND PROCESSES FOR GENERATING CHEMILUMINESCENCE EMPLOYING SAID COMPOSITIONS | AMERICAN CYANAMID COMPANY (US) | 1981-10-07 | — | — | EP | disclosed |
| US-4288592-A | Process for preparing amides by reaction in presence of molecular sieve | AMERICAN CYANAMID COMPANY (US) | 1981-09-08 | — | — | US | disclosed |
| US-4226738-A | SUPERIOR LIGHT INTENSITY, QUANTUM EFFICIENT, AND LONG-LASTING | AMERICAN CYANAMID COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0010844-A1 | Novel N,N'-bis(trifluoromethylsulfonyl)oxamides, chemiluminescent compositions containing them and processes for generating chemiluminescence employing said compositions | AMERICAN CYANAMID COMPANY (US) | 1980-05-14 | — | — | EP | disclosed |