SCHEMBL6000979

SCHEMBL6000979

O=S(=O)(c1ccccc1Cl)c1cc(Cl)ccc1NS(=O)(=O)C(F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.51
CNR2 P34972 7/20 0.46
CNR1 P21554 4/20 0.46
PTGES2 Q9H7Z7 1/20 0.46
CYP2C9 P11712 3/20 0.46
CA1 P00915 1/20 0.45
MCL1 Q07820 4/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
SLC22A12 Q96S37 1/20 0.44
PTGS1 P23219 3/20 0.44
PTGS2 P35354 3/20 0.44
HSD11B1 P28845 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11330348 0.78 CA2 (0.67) CA2CNR2CA1MCL1HPGD
SCHEMBL10934176 0.74 PTGS1 (0.64) CA2CA1MCL1TSHRSLC22A12
SCHEMBL6001677 0.74 CA2 (0.48) CA2CNR2CA1SLC22A12PTGS1
SCHEMBL11133599 0.71 CA2 (0.70) CA2PTGES2CA1SLC22A12PTGS1
SCHEMBL2080151 0.71 CA2 (0.45) CA2CA1PTGS1PTGS2
SCHEMBL30697126 0.70 HSD11B1 (0.59) TSHRHSD11B1
SCHEMBL248010 0.70 HSD11B1 (0.59) TSHRHSD11B1
SCHEMBL2079574 0.70 CA2 (0.49) CA2CA1SLC22A12PTGS1PTGS2
SCHEMBL2123876 0.70 HSD11B1 (0.59) TSHRHSD11B1
SCHEMBL1414850 0.70 CA2 (0.72) CA2PTGES2CA1SLC22A12PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060281695-A1 Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives SCHERING-PLOUGH ANIMAL HEALTH CORPORATION 2006-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060281695-A1 Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives ELANE, CTRL, PIGO CA2 3839/4885CNR2 1110/4885CNR1 508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.