Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341395 | 0.86 | HRH3 (0.50) | HRH3KCNH2KDM4EALDH1A1 | |
| SCHEMBL11341383 | 0.84 | HTR4 (0.55) | HRH3KDM4EALDH1A1HTR4CYP2D6 | |
| SCHEMBL4506214 | 0.82 | HRH3 (0.55) | MAOBHRH3KCNH2 | |
| SCHEMBL4498814 | 0.76 | MAOB (0.49) | MAOBHRH3KDM4EALDH1A1 | |
| SCHEMBL11344876 | 0.76 | KDM4E (0.48) | HRH3KDM4EALDH1A1TSHR | |
| SCHEMBL4490641 | 0.74 | HRH3 (0.49) | MAOBHRH3 | |
| SCHEMBL6268708 | 0.74 | KDM4E (0.51) | HRH3KDM4EALDH1A1HTR4 | |
| SCHEMBL4498291 | 0.74 | NPC1 (0.54) | MAOBHRH3KDM4EALDH1A1 | |
| SCHEMBL4492506 | 0.73 | HRH3 (0.52) | MAOBHRH3KCNH2 | |
| SCHEMBL11331256 | 0.72 | ALDH1A1 (0.50) | MAOBKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304831-A | ELECTROGRAPHY; COPIES | RICOH CO., LTD. (JP) | 1981-12-08 | — | — | US | claimed |
| US-4304831-A | ELECTROGRAPHY; COPIES | RICOH CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4225662-A | 5-(ACETOACETAMIDO)BENZIMIDAZOLIN-2-ONE YELLOW COUPLERS | RICOH COMPANY, LTD. (JP) | 1980-09-30 | — | — | US | disclosed |