Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 5/20 | 0.61 |
| ▸ | GNB1 | P62873 | 5/20 | 0.61 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.55 |
| ▸ | P2RY4 | P51582 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634834 | 0.90 | GNG2 (0.49) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL8634052 | 0.90 | GNG2 (0.49) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL8634821 | 0.90 | GNG2 (0.60) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL8634590 | 0.86 | GNG2 (0.61) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL8021024 | 0.82 | GNG2 (0.64) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL11319865 | 0.82 | GNG2 (0.64) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL14355357 | 0.81 | GNG2 (0.62) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL8636372 | 0.80 | GNG2 (0.48) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL8632318 | 0.80 | GNG2 (0.48) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL11678111 | 0.80 | GNG2 (0.48) | GNG2GNB1PHLPP2P2RY4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294580-A | HYDROXYL OR NITROGEN, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |
| US-4255325-A | AZO, ANTHRAQUINONE, FORMAZANE, AND PHTHALOCYANINE DYES; COLOR AND WASHFASTNESS; AMINO HALO TRIAZINE CARBAZIDE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-10 | — | — | US | disclosed |