Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 5/20 | 0.64 |
| ▸ | GNB1 | P62873 | 5/20 | 0.64 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.60 |
| ▸ | P2RY4 | P51582 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NSD2 | O96028 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021024 | 0.86 | GNG2 (0.64) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL14355357 | 0.85 | GNG2 (0.62) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL13214108 | 0.84 | GNG2 (0.64) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL11333865 | 0.84 | ALDH1A1 (0.79) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL8634821 | 0.84 | GNG2 (0.60) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL3028166 | 0.83 | ALDH1A1 (0.77) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL30205040 | 0.83 | ALDH1A1 (0.77) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL9844573 | 0.82 | GNG2 (0.61) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL11330686 | 0.82 | GNG2 (0.61) | GNG2GNB1PHLPP2P2RY4ALDH1A1 | |
| SCHEMBL8630004 | 0.82 | GNG2 (0.66) | GNG2GNB1PHLPP2P2RY4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289496-A | LOW LIQUID TO MATERIAL RATIO RESULTING IN UNIFORMITY OF FINISHING | SANDOZ LTD. (CH) | 1981-09-15 | — | — | US | disclosed |