Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 4/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13314418 | 1.00 | APEX1 (0.47) | APEX1ZDHHC20ZDHHC2EGFRKDM4E | |
| SCHEMBL157106 | 0.98 | APEX1 (0.48) | APEX1ZDHHC20ZDHHC2EGFRKDM4E | |
| SCHEMBL109519 | 0.94 | APEX1 (0.44) | APEX1ZDHHC20ZDHHC2EGFRKDM4E | |
| SCHEMBL22187118 | 0.92 | APEX1 (0.51) | APEX1ZDHHC20ZDHHC2EGFRKDM4E | |
| SCHEMBL109577 | 0.85 | SMN1; SMN2 (0.41) | APEX1SMN1; SMN2ALDH1A1PYGLTAAR1 | |
| SCHEMBL21610956 | 0.85 | APEX1 (0.49) | APEX1ZDHHC20ZDHHC2EGFRKDM4E | |
| SCHEMBL21731701 | 0.84 | ZDHHC20 (0.63) | APEX1ZDHHC20ZDHHC2EGFREPHX1 | |
| SCHEMBL85840 | 0.84 | KDM4E (0.64) | APEX1ZDHHC20ZDHHC2EGFRKDM4E | |
| SCHEMBL19363595 | 0.84 | ZDHHC20 (0.63) | APEX1ZDHHC20ZDHHC2EGFREPHX1 | |
| SCHEMBL8511129 | 0.84 | ZDHHC20 (0.63) | APEX1ZDHHC20ZDHHC2EGFREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424491-A2 | FILM FORMER IN HAIR DYES | Henkel AG & Co. KGaA (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010124897-A2 | FILM FORMER IN HAIR DYES | HENKEL AG & CO. KGAA (DE) | 2010-11-04 | — | — | WO | disclosed |