Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22187118 | 0.92 | APEX1 (0.51) | KDM4EMAPK1HIF1AAPEX1ZDHHC20 | |
| SCHEMBL21610956 | 0.85 | APEX1 (0.49) | KDM4EMAPK1HIF1AAPEX1ZDHHC20 | |
| SCHEMBL113308 | 0.84 | APEX1 (0.47) | KDM4EMAPK1HIF1AAPEX1ZDHHC20 | |
| SCHEMBL19363595 | 0.84 | ZDHHC20 (0.63) | APEX1ZDHHC20ZDHHC2EGFR | |
| SCHEMBL8511129 | 0.84 | ZDHHC20 (0.63) | APEX1ZDHHC20ZDHHC2EGFR | |
| SCHEMBL13314418 | 0.84 | APEX1 (0.47) | KDM4EMAPK1HIF1AAPEX1ZDHHC20 | |
| SCHEMBL21731701 | 0.84 | ZDHHC20 (0.63) | APEX1ZDHHC20ZDHHC2EGFR | |
| SCHEMBL108156 | 0.82 | PAOX (0.57) | KDM4EMAPK1HIF1APAOXAPEX1 | |
| SCHEMBL13314415 | 0.82 | PAOX (0.57) | KDM4EMAPK1HIF1APAOXAPEX1 | |
| SCHEMBL7532607 | 0.82 | ZDHHC20 (0.60) | APEX1ZDHHC20ZDHHC2EGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129529-B2 | UV excitable fluorescent energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110077415-A1 | UV Excitable Fluorescent Energy Transfer Dyes | Life Technologies Corporation (US) | 2011-03-31 | — | — | US | disclosed |
| US-7888507-B2 | UV excitable fluorescent energy transfer dyes | APPLIED BIOSYSTEMS, LLC | 2011-02-15 | — | — | US | disclosed |
| US-7550570-B2 | Labeling nucleotide sequences with rhodamine dye | APPLIED BIOSYSTEMS, LLC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-20090093623-A1 | 4,7-DICHLORORHODAMINE DYES | APPLIED BIOSYSTEMS INC. (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090062543-A1 | UV EXCITABLE FLUORESCENT ENERGY TRANSFER DYES | APPLIED BIOSYSTEMS INC. (US) | 2009-03-05 | — | — | US | disclosed |
| US-20090031506-A1 | UV Excitable Fluorescent Energy Transfer Dyes | APPLERA CORPORATION (US) | 2009-02-05 | — | — | US | disclosed |
| US-7402671-B2 | UV excitable fluorescent energy transfer dyes | APPLERA CORPORATION (US) | 2008-07-22 | — | — | US | disclosed |
| US-7378517-B2 | UV excitable energy transfer reagents | APPLERA CORPORATION (US) | 2008-05-27 | — | — | US | disclosed |
| US-7179906-B2 | Asymmetric benzoxanthene dyes | APPLERA CORPORATION (US) | 2007-02-20 | — | — | US | disclosed |
| US-7169939-B2 | Energy transfer dyes with enhanced fluorescence | APPLERA CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
| US-7157572-B2 | UV excitable energy transfer reagents | APPLERA CORPORATION (US) | 2007-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062543-A1 | UV EXCITABLE FLUORESCENT ENERGY TRANSFER DYES | SLC46A1, SLC43A3, SLC25A4 | KDM4E 3624/4885MAPK1 3417/4885HIF1A 3329/4885 |
| US-20090093623-A1 | 4,7-DICHLORORHODAMINE DYES | POLL, FPR3, DRD4 | KDM4E 1350/4885MAPK1 3651/4885HIF1A 2854/4885 |
| US-20110077415-A1 | UV Excitable Fluorescent Energy Transfer Dyes | SLC46A1, SLC43A3, SLC25A4 | KDM4E 3624/4885MAPK1 3417/4885HIF1A 3329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.